Impact of preformed donor-specific anti-HLA antibodies on pancreatic islet transplantation outcomes: do they matter as they do in solid organ transplantation?
BackgroundPreformed donor-specific anti-HLA antibodies (DSA) are a major risk factor for antibody-mediated rejection and graft failure in kidney, heart, lung, and other vascularized solid organ transplants. Their clinical significance in pancreatic isl…