Comprehensive analysis of RFC4 as a potential biomarker for regulating the immune microenvironment and predicting immune therapy response in lung adenocarcinoma
BackgroundReplication factor C subunit 4 (RFC4) is crucial for initiating DNA replication via DNA polymerase δ and ϵ and is overexpressed in various cancers. However, its relationship with the tumor immune microenvironment (TIME), and immunotherapy res…