Increased reporting of interstitial pneumonitis with combined EGFR-TKI and PD-1/PD-L1 inhibitor therapy in NSCLC: a pharmacovigilance analysis of 67,818 reports
ImportanceBoth epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) and PD-1/PD-L1 inhibitors are widely used in non–small cell lung cancer (NSCLC). The safety of their combination, particularly the risk of interstitial pneumonitis (…