Sex-specific effects of resveratrol and metformin on mitochondrial function and inflammatory activation in a TNF-α-driven human iPSC-derived endothelial dysfunction model
Endothelial dysfunction and mitochondrial impairment are key early events in atherogenesis and exhibit sex-specific patterns. Resveratrol and metformin are cardiometabolic modulators with antioxidative and mitochondrial effects, but their sex-dependent…