NF-κB/NFAT signaling contributes to B7-H3 TRuC-T cell cytotoxicity and supports a reporter platform for glioblastoma immunotherapy
IntroductionGlioblastoma (GBM), the most prevalent and aggressive malignant tumor of the nervous system, presents a formidable clinical challenge due to its rapid progression and extremely poor prognosis. T cell receptor fusion constructs (TRuC) -T cel…