The clinical utility of autoantibodies in systemic sclerosis: a review with a focus on cohort differences and standardization
BackgroundSystemic sclerosis (SSc) is clinically heterogeneous. Disease-specific autoantibodies—anticentromere (ACA), anti–topoisomerase I (ATA/Scl-70), and anti–RNA polymerase III (RNAP III)—are central to classification and organ-risk prediction. Bey…