The LVI Component Hypothesis: the lymphatic-to-vascular invasion ratio as an enrichment biomarker for therapy with PD-L1×VEGF-A bispecific antibodies
Lymphovascular invasion (LVI) describes intravasated tumor cells within intratumoral lymphatic or blood vessels. LVI is reported routinely on pathologic examination because it is prognostic for reduced disease-free and overall survival across many soli…