Risk prediction of PLA2R-Ab-negative membranous nephropathy: an interpretable multicenter machine learning model

BackgroundApproximately 10%–30% patients with biopsy-proven membranous nephropathy (MN) are seronegative for anti-phospholipase A2 receptor antibody (PLA2R-Ab). Only ~5% are truly non-PLA2R MN and are associated with alternative antigens (e.g., THSD7A)…

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