The challenge of one billion adjuvanted vaccine doses: evaluating scalability, sustainability, and supply capacity of Quillaja saponin QS-21 for large-scale vaccine demand

The biomass of Quillaja saponaria is a well-characterized source of triterpenic saponins, a family of amphiphilic glycosides with broad industrial and biomedical relevance. Among these, the highly purified fraction QS-21, and the related fractions QHA …

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