Granzyme B from mast cells contributes to choroidal neovascularization in a model of wet age-related macular degeneration
PurposeWet age-related macular degeneration (AMD) is characterized by choroidal neovascularization (CNV), yet current anti-VEGF therapies are ineffective in many patients. This study investigates the role of mast cell–derived granzyme B (GzmB), a serin…