B-cell immune repertoire sequencing in tobacco cigarette smoking, vaping, and chronic obstructive pulmonary disease in the COPDGene cohort
RationaleCigarette smoking (CS) impairs B-cell function and antibody production, increasing infection risk. The impact of e-cigarette use (‘vaping’) and combined CS and vaping (‘dual-use’) on B-cell activity is unclear.ObjectiveTo examine B-cell recept…