MZB1 expression levels are associated with long-term maintenance of high anti-HBs titers: single-cell RNA-seq with validation by nested case-control and intervention studies
BackgroundApproximately 5–10% of healthy, immunocompetent individuals are low- or non-responders to the HepB vaccine. The mechanism remains obscured. Among responders, immunity may wane over time, becoming undetectable in some. However, in some vaccine…