Serum paraoxonase-1 as a marker of oxidative stress and pulmonary dysfunction in sarcoidosis: association with disease activity and prognostic potential
ObjectivesSarcoidosis is a multisystem granulomatous disorder characterized by an oxidative imbalance and inflammatory activation. Paraoxonase-1 (PON1) is a high-density lipoprotein–associated antioxidant enzyme that plays a protective role against oxi…