Mohammed Dashti

BackgroundType 1 diabetes (T1D) clusters within families, yet shared genetic susceptibility does not fully explain discordance among relatives. We investigated whether single CpG methylation differences recur independently across multiplex T1D families…

BackgroundGenome-wide association studies have implicated the human leukocyte antigen/major histocompatibility complex (HLA/MHC) region in amyotrophic lateral sclerosis (ALS) susceptibility, and immune dysregulation is increasingly recognised as a modi…