Autoantibodies against interleukin-1 receptor antagonist in Still’s disease in adult patients, data from a multicenter cohort study

ObjectivesEmerging evidence supports the presence of autoantibodies targeting interleukin-1 receptor antagonist (IL-1Ra), a regulator of IL-1 signaling, in adult-onset Still’s disease (AOSD). However, existing data are limited by small cohorts and pote…

Real-world therapeutic strategies in active adult-onset Still’s disease: clinical insights from the GIRRCS-AOSD study group

ObjectivesTo evaluate the therapeutic management of patients with active adult-onset Still’s disease (AOSD) in a multicentre real-world setting and to provide and compare current real-world treatment strategies with existing recent international recomm…

Application of machine learning techniques to explore the occurrence of macrophage activation syndrome in Still’s disease: results from the GIRRCS AOSD Study Group and the AIDA Network Still’s Disease Registry

ObjectivesThis study aims to explore the application of machine learning techniques in assessing macrophage activation syndrome (MAS) in Still’s disease.MethodsA multicenter, observational, prospective study was conducted, including patients with Still…

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