Zinc and metallothionein dysregulation in B cells in multiple sclerosis, with disease-specific CXCR3+/CXCR3⁻ divergence in blood
IntroductionMultiple sclerosis (MS) is associated with compartmentalized B-cell responses in the cerebrospinal fluid (CSF), where CXCR3+ B cells contribute to intrathecal immune activity and tissue injury. Zinc is an important regulator of immune-cell …