Mincle-dependent Th17 adjuvanticity requires TNFR1 signaling in myeloid cells
Successful induction of protective T cells by recombinant protein vaccines requires adjuvants. The liposomal adjuvant system CAF01 induces robust Th17 responses in mice. CAF01 contains the synthetic glycolipid trehalose-6,6-dibehenate (TDB), whose reco…