Shah Faisal
Nurr1 deficiency orchestrates a coupled liver–gut pathological axis revealed by multi-omics and deep-learning histopathology
The nuclear receptor Nurr1 (NR4A2) is a transcriptional regulator of inflammatory homeostasis, but its systemic effects on orchestrating inter-organ communications are largely unknown. Here we show that Nurr1 haplo-insufficiency results in a lethal cou…