Shanshan Wang – InmunoES

Shared immune perturbations in hepatocellular carcinoma-depression comorbidity and synergistic immunotherapeutic effects of fluoxetine combined with anti-PD-1

25 de September de 2026 by Shanshan Wang

BackgroundHepatocellular carcinoma (HCC) often coexists with depression, elevating patient mortality by 39%. The tryptophan metabolic axis bridges tumor and neuropsychiatric immune dysfunction, yet the immunometabolic crosstalk underlying HCC-depressio…

Integrated bioinformatics and machine learning identify early diagnostic biomarkers for MAFLD with comorbid psoriasis

15 de April de 2026 by Shanshan Wang

BackgroundPsoriasis and metabolic dysfunction–associated fatty liver disease (MAFLD) share pathological features such as chronic inflammation, immune dysregulation, and metabolic disturbance. Increasing evidence suggests biological crosstalk between th…