Shuang Ma Rectal cancer exhibits prominent anatomical and molecular heterogeneity, shaping a tumor microenvironment that determines responsiveness to immune checkpoint inhibitors (ICIs). Though ICIs exert robust anti-tumor effects on dMMR/MSI-H rectal tumors, ov…
Cancer immunotherapy has revolutionized cancer treatment, yet its effects extend far beyond tumor eradication. Accumulating evidence indicates that immunotherapy-associated skeletal muscle dysfunction represents a complex, cross-organ pathological proc…
Cancer immunotherapy, which leverages the immune system to target neoplastic cells, has undergone significant transformation in recent. However, immunotherapy may have negative effects on skeletal muscle function, causing muscle wasting and functional …
The intricate interaction between skeletal muscle biomechanics, the tumor microenvironment, and immunotherapy constitutes a pivotal research focus oncology. This work provides a comprehensive review of methodologies for evaluating skeletal muscle biome…
