Association of elevated serum active IL-18 levels with cytokine profiles and clinical features in adult-onset still’s disease
IntroductionInflammasome-mediated activation of interleukin (IL)-1β and IL-18 plays a key role in the pathogenesis of adult-onset Still’s disease (AOSD), a systemic autoinflammatory disorder. The cleaved free active form of IL-18 may more accurately re…