Association of elevated serum active IL-18 levels with cytokine profiles and clinical features in adult-onset still’s disease

IntroductionInflammasome-mediated activation of interleukin (IL)-1β and IL-18 plays a key role in the pathogenesis of adult-onset Still’s disease (AOSD), a systemic autoinflammatory disorder. The cleaved free active form of IL-18 may more accurately re…

Serum Mac-2 binding protein glycosylation isomer and galectin-3 levels in adult-onset Still’s disease and their association with cytokines

BackgroundAutoinflammation with cytokine dysregulation may be implicated in the pathophysiology of adult-onset Still’s disease (AOSD); however, the relationship between galectins and cytokines in patients with active AOSD remains unknown. We aimed to e…

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