Kangxianhuanji formula and its component rutin ameliorate acute exacerbation of idiopathic pulmonary fibrosis by targeting GLUT1 to suppress HIF-1α–mediated glycolysis
BackgroundAcute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is a life-threatening condition characterized by uncontrolled inflammation and progressive fibrosis, with limited effective therapies. Kangxianhuanji Formula (KHF), a traditional he…