APOE-associated lipid-handling macrophages in hepatocellular carcinoma: ligand–receptor communication and host Apoe-linked myeloid remodeling
BackgroundHepatocellular carcinoma (HCC) arises in the liver, an organ with active lipid metabolism, and is accompanied by marked myeloid-cell remodeling. Whether lipid-handling macrophage states are enriched in HCC and how they relate to candidate lig…