Prognostic value of metal-based ferroptosis and cuproptosis genes and score in lower grade gliomas

BackgroundFerroptosis and Cuproptosis are newly defined forms of cell death. Despite distinct mechanisms, both involve metabolic processes in the TCA cycle and downstream pathways, crucial for anticancer immunity.MethodsWe evaluated Iron (Fe) and Coppe…

Integrative analysis of T cell-associated markers in Ewing sarcoma reveals prognostic signatures and immune dynamics

BackgroundEwing sarcoma (ES) is a rare and aggressive pediatric bone malignancy with poor prognosis, driven by therapy-resistant tumor microenvironments (TME). The TME plays a critical role in tumor progression through a complex and dynamic network of …

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