Venkatesh Kumaresan

Systems biology approach unveils the cellular and molecular mechanisms of formalin-inactivated whole cell vaccine-induced protective immunity against Coxiella burnetii infection in mice

4 de June de 2026 by Venkatesh Kumaresan

BackgroundThe formalin-inactivated Coxiella burnetii virulent phase I vaccine (PIV) has been shown to be more protective than the avirulent phase II vaccine (PIIV) against virulent C. burnetii challenge in animal models. However, the cellular and molec…

Editorial: Exploring immune evasion and vaccine strategies in host-pathogen interactions

14 de April de 2026 by Venkatesh Kumaresan

Role of dual specificity phosphatase 1 in influencing inflammatory pathways in macrophages modulated by Borrelia burgdorferi lipoproteins

7 de April de 2026 by Venkatesh Kumaresan

Borrelia burgdorferi (Bb), the spirochetal agent of Lyme disease, has a large array of lipoproteins that play a significant role in mediating host-pathogen interactions within ticks and vertebrates. While prior work has established that borrelial lipop…