An endoplasmic reticulum stress- and Golgi apparatus-related signature reveals immune microenvironment remodeling and MUC16-driven PI3K/AKT activation in lung adenocarcinoma
BackgroundLung adenocarcinoma (LUAD), the most prevalent histological subtype of non-small cell lung cancer (NSCLC), is characterized by substantial clinical heterogeneity and a frequent propensity to acquire resistance to targeted therapies. Accumulat…