Case Report: Anti-PD-1 therapy as a catalyst for the rapid transformation of a hepatic nodule into HCC: a “soil and seed” paradox in metachronous triple primary malignancies?
Multiple primary malignancies (MPMs) are increasingly recognized, yet the impact of immune checkpoint inhibitors (ICIs) on the evolution of metachronous tumors remains poorly understood. Here, we report a rare case of metachronous triple primary malign…