Xiaoqin Liu – InmunoES

Integrative single-cell and bulk transcriptomic analyses identify a microglia-associated NAGLU signature linked to disulfidptosis-associated transcriptional patterns after spinal cord injury

14 de August de 2026 by Xiaoqin Liu

BackgroundSpinal cord injury (SCI) induces profound neuroinflammatory responses and extensive cellular remodeling within the injured spinal cord. Disulfidptosis, a recently identified form of regulated cell death associated with disulfide stress, has b…

Deciphering hub genes and immune landscapes related to neutrophil extracellular traps in spinal cord injury: insights from integrated bioinformatics analyses and experiments

5 de March de 2026 by Xiaoqin Liu

BackgroundSpinal cord injury (SCI) is a debilitating neurological condition that results in severe motor, sensory, and autonomic dysfunction, imposing a considerable burden on affected individuals and healthcare systems. Neutrophil extracellular traps …

Methyl-CpG-binding domain protein 2 epigenetically represses monocyte HLA-DR expression and promotes immune paralysis in HBV-related acute-on-chronic liver failure

18 de February de 2026 by Xiaoqin Liu

Chronic hepatitis B (CHB) is the leading cause of acute-on-chronic liver failure (ACLF) in China and other Asian countries. A defining immunopathological feature of hepatitis B virus-related ACLF (HBV-ACLF) is immune paralysis, which significantly incr…