Yao Lu BackgroundViral infection induces host cells to enter a state of “virus-induced senescence (VIS)”, which provides a stable cellular environment for viral replication. However, it is unclear about the molecular mechanism of this process. Here, we identi…
BackgroundPyroptosis, an inflammatory form of programmed cell death, contributes to intestinal inflammation in inflammatory bowel disease (IBD), but the key cell types and regulatory genes remain unclear.MethodsWe analyzed single-cell RNA-seq data from…
IntroductionInflammatory bowel disease (IBD) is a chronic inflammatory condition of the intestine, for which no cure currently exists. The gut microbiota play a critical role in ameliorating IBD, and Eubacterium limosum has emerged as a potential probi…
The gut microbiome critically regulates antitumor immunity through its metabolic byproducts, which serve as pivotal mediators of host-microbe crosstalk in tumor immunotherapy. This review synthesizes cutting-edge evidence on how microbial metabolites—i…
