Knockout of p47phox inhibits deep vein thrombosis by regulating the PAC-1/FNG/MAC-1 signaling axis and ameliorating mitochondrial dysfunction
ObjectiveTo elucidate the role and molecular mechanism of the NADPH oxidase key subunit p47phox in deep vein thrombosis (DVT) formation by investigating its regulatory effects on neutrophil extracellular traps (NETs) generation, the PAC-1/FNG/MAC-1 sig…