Yuan Tian BackgroundDevelopment of de novo donor-specific antibodies (dnDSA) remains a key risk factor for antibody-mediated rejection and graft loss in kidney transplantation. The PIRCHE-T2 model estimates immunogenicity by predicting donor-derived HLA peptides…
BackgroundAntibody-mediated rejection (ABMR) is a major cause of graft loss in kidney transplantation, often associated with de novo donor-specific antibodies (dnDSA). The detection of clinically relevant dnDSA relies on evaluating reactivity in single…
BackgroundDonor-derived cell-free DNA (dd-cfDNA) is a promising non-invasive biomarker for detecting graft injury in solid organ transplant recipients. Elevated dd-cfDNA levels are strongly associated with rejection and graft injury, especially antibod…
