Yuanyuan Yang

Inflammatory bowel disease (IBD) is sustained not only by dysregulated adaptive immunity, but also by profound disruption of the intestinal macrophage compartment. In healthy mucosa, macrophages maintain immune tolerance, support epithelial integrity, …

Human atherosclerosis is increasingly recognized as a spatially organized inflammatory disease in which macrophages act as central regulators of lesion evolution rather than as a uniform foam-cell population. Recent single-cell and spatial profiling st…