Histological grading of tertiary lymphoid structures correlates with renal impairment and adverse outcomes in ANCA-associated glomerulonephritis

BackgroundTertiary lymphoid structures (TLS) are organized immune aggregates that develop in non-lymphoid tissues during chronic inflammation and are associated with adverse outcomes in various kidney diseases. Their role in antineutrophil cytoplasmic …

The predictive value of baseline systemic inflammation response index and systemic immune-inflammation index for the risk of infection within 6 months following initial immunosuppressive treatment in patients with ANCA-associated vasculitis

BackgroundPatients with ANCA-associated vasculitis (AAV) face a high risk of severe infections, particularly within the first six months of immunosuppressive therapy, contributing significantly to early mortality. The systemic immune-inflammation index…

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