Integrative analysis of transcriptomics, single-cell RNA sequencing, and GraphBAN identifies de novo lipogenesis-associated genes and their potential roles in diabetic retinopathy
BackgroundDiabetic retinopathy (DR) represents a key microvascular disorder resulting from prolonged diabetes mellitus. Hyperglycemia, a common driver of diabetes-related vision loss, can pathologically activate de novo lipogenesis (DNL); however, the …