Identification of Wnt/β-catenin- and immune-related genes in hepatic ischemia-reperfusion injury using bulk transcriptomics, single-cell RNA sequencing, and a murine model
IntroductionHepatic ischemia-reperfusion injury (HIRI) is a major complication following liver transplantation (LT), contributing to graft dysfunction and rejection. The roles of the Wnt/β-catenin signaling pathway and immune responses in LT-related HI…