Evaluating the toxicity profile of combination immune checkpoint inhibitors: a disproportionality analysis of real-world adverse events from the FDA Adverse Event Reporting System for tremelimumab, durvalumab, ipilimumab, and nivolumab
BackgroundAs one of the therapeutic modalities for treating tumors, immune checkpoint inhibitors (ICIs) have gained widespread application in clinical practice, including non-small cell lung cancer, melanoma, head and neck squamous cell carcinoma, hepa…