Case Report: Hemophagocytic lymphohistiocytosis secondary to Escherichia coli infiltration of bone marrow in a patient with seronegative rheumatoid arthritis treated with low-dose methotrexate
Hemophagocytic lymphohistiocytosis (HLH) is a disorder characterized by dysregulated immune activation triggered by various etiologies, leading to excessive inflammatory responses, cytokine storm, and subsequent organ dysfunction. While the presence of…