Sustained abnormal bilirubin and leukocyte levels after ERCP with acute suppurative obstructive cholangitis: a case report with 2 months follow-up observation

Acute Suppurative Obstructive Cholangitis (AOSC) typically resolves post-ERCP. However, a 53-year-old male had persistent hyperbilirubinemia and leukocytosis (WBC 28.12×109/L) along with marked eosinophilia (20.26×109/L) despite standard antibiotic the…

Case Report: Transient perivascular inflammation of the carotid artery syndrome: a rare etiology of self-limiting carotidynia

ObjectivesTransient perivascular inflammation of the carotid artery (TIPIC) syndrome is a recently recognized clinicoradiological entity that has not yet been formally incorporated into established disease classifications. It is frequently overlooked i…

Ruxolitinib reverses systemic vasculitis driven by JAK2 V617F–mutated essential thrombocythemia: a case report

BackgroundVasculitis associated with myeloproliferative neoplasms is rare, and reports on its treatment are limited. Herein, we report a case of Janus Kinase2 (JAK2) V617F mutation–positive essential thrombocythemia (ET) associated with vasculitis.Case…

Case Report: Localized hyperinflammatory response in the bulla after mosquito bites in a patient with systemic lupus erythematosus

A patient with systemic lupus erythematosus developed localized swelling with blistering after mosquito bites. A complete blood count showed eosinophils were 1.09 × 109/L (13.9%). Total IgE was more than 5,000 KU/L. Examination of the blister fluid sho…

Case Report: Rapid progression of inflammation-driven coronary artery lesions in a normolipidemic patient with ANCA-associated vasculitis complicated by Stanford type A aortic dissection

BackgroundAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune small- to medium-vessel vasculitis. Reports of rapidly progressive left main/left anterior descending (LM/LAD) disease under normolipidemic condit…

Case report: Thymoma-associated GAD65 autoimmunity: a unifying mechanism for multi-organ injury involving nervous, endocrine, and renal systems

Thymomas are well-established disruptors of central immune tolerance, yet their capacity to drive systemic autoimmunity via a single autoantigen remains incompletely characterized. We report a 59-year-old male who, following resection of a Masaoka stag…

Multidisciplinary management of refractory Kawasaki disease with bilateral giant coronary artery aneurysms and latent tuberculosis infection: a case report focusing on immune–coagulation–infection crosstalk

BackgroundThe management of refractory Kawasaki disease (KD) with giant coronary artery aneurysms (CAAs) complicated by latent tuberculosis infection (LTBI) represents a formidable “triple challenge”: it requires balancing aggressive inflammation contr…

Neurological graft-versus-host disease with MOG antibody positivity after allogeneic stem cell transplantation: a case report

BackgroundCentral nervous system (CNS) involvement is recognized as a distinct manifestation of chronic GVHD (cGVHD). Myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) is an autoimmune disorder targeting the CNS. Therefore, the oc…

Immune profiling-informed immunomodulation associated with gestational extension in early-onset preeclampsia with monochorionic twins: a case report

BackgroundEarly-onset preeclampsia (EOPE) is associated with placental malperfusion and systemic endothelial dysfunction. Maternal immune dysregulation has been implicated in EOPE, but immune findings obtained during severe disease are descriptive and …

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