Connective tissue disease (CTD) is one of the common autoimmune diseases (AIDs). Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disease characterized by peripheral blood monocytosis and bone marrow dysplasia, and it is frequ…
Cytokine storm syndrome (CSS) represents a severe systemic inflammatory condition precipitated by the hyperactivation of immune cells and the consequent excessive release of cytokines, triggered by various factors. This report details the case of a 23-…
Immunoglobulin G4-related disease (IgG4-RD) is a systemic, immune-mediated fibro-inflammatory disorder with the potential to affect multiple organs, with the kidney being the most commonly involved organ, typically presenting as IgG4-related tubulointe…
Fibrin-associated large B-cell lymphoma (FA-LBCL) is recognized as a distinct entity in the 5th edition of the World Health Organization (WHO) classification of hematolymphoid tumors. It is a rare Epstein–Barr virus (EBV)-positive B-cell neoplasm that …
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is an autoimmune disorder affecting the central nervous system (CNS), characterized by the presence of autoantibodies against MOG (MOG-IgG) in serum or cerebrospinal fluid (C…
IgG4-related disease (IgG4-RD) is a rare fibro-inflammatory condition with scarce data on its clinical spectrum and management in the pediatric population.We present a single-center observational study of six children with clinically and morphologicall…
SMARCA4-deficient undifferentiated cervical tumor is highly malignant and responds poorly to conventional treatments, leading to a very poor prognosis. We report a case involving a primary cervical lesion measuring 9.8 cm, managed using a strategy of “…
High-grade neuroendocrine carcinoma (NEC) can be difficult to diagnose, particularly when conventional neuroendocrine (NE) markers are weakly expressed or absent. This challenge is particularly pronounced in NE-low tumors with lineage-defining transcri…
IntroductionImmune checkpoint inhibitors (ICIs), including PD-1 inhibitors, have significantly improved survival outcomes in patients with melanoma; however, serious adverse events may occur as a consequence of immune dysregulation. Autoimmune hemolyti…
IntroductionVEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) syndrome represents a recently identified systemic condition, and its diagnosis and management carry significant clinical ramifications. Despite advancements in understanding …
