ObjectiveTo investigate the etiology of recurrent severe pneumonia and pleural effusion in a pediatric patient through pathogenic gene testing and bioinformatics analysis.MethodsClinical characteristics and laboratory findings were retrospectively revi…
Neuronal intranuclear inclusion disease (NIID) can initially present with gastrointestinal symptoms as the sole or primary manifestation for decades before neurological signs emerge. We report the case of a 61-year-old woman with a 22-year history of d…
Nimotuzumab, a humanized immunoglobulin G1 monoclonal antibody, is mainly used in combination with radiotherapy for the treatment of stage III/IV nasopharyngeal carcinoma (NPC) or locally advanced head and neck squamous-cell carcinoma (HNSCC) with posi…
Undifferentiated small round cell sarcoma (USRCS) are a rare, aggressive group of tumors associated with rapid progression, metastasis, and poor prognosis. Preoperative diagnosis remains elusive, particularly for extraosseous variants, and effective tr…
Generalized pustular psoriasis (GPP) is a rare, potentially life-threatening inflammatory disease characterized by neutrophilic pustules and systemic inflammation. We report a case of severe GPP triggered by SARS-CoV-2 infection in a 46-year-old woman …
Immunoglobulin G4-related disease (IgG4-RD) is a chronic, systemic fibroinflammatory autoimmune disorder characterized by multi-organ involvement, elevated serum IgG4 levels, and dense infiltration of IgG4+ plasma cells. The disease can affect nearly a…
Acute Suppurative Obstructive Cholangitis (AOSC) typically resolves post-ERCP. However, a 53-year-old male had persistent hyperbilirubinemia and leukocytosis (WBC 28.12×109/L) along with marked eosinophilia (20.26×109/L) despite standard antibiotic the…
ObjectivesTransient perivascular inflammation of the carotid artery (TIPIC) syndrome is a recently recognized clinicoradiological entity that has not yet been formally incorporated into established disease classifications. It is frequently overlooked i…
BackgroundVasculitis associated with myeloproliferative neoplasms is rare, and reports on its treatment are limited. Herein, we report a case of Janus Kinase2 (JAK2) V617F mutation–positive essential thrombocythemia (ET) associated with vasculitis.Case…
A patient with systemic lupus erythematosus developed localized swelling with blistering after mosquito bites. A complete blood count showed eosinophils were 1.09 × 109/L (13.9%). Total IgE was more than 5,000 KU/L. Examination of the blister fluid sho…
