Case Report: Rapid progression of inflammation-driven coronary artery lesions in a normolipidemic patient with ANCA-associated vasculitis complicated by Stanford type A aortic dissection

BackgroundAntineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune small- to medium-vessel vasculitis. Reports of rapidly progressive left main/left anterior descending (LM/LAD) disease under normolipidemic condit…

Case report: Thymoma-associated GAD65 autoimmunity: a unifying mechanism for multi-organ injury involving nervous, endocrine, and renal systems

Thymomas are well-established disruptors of central immune tolerance, yet their capacity to drive systemic autoimmunity via a single autoantigen remains incompletely characterized. We report a 59-year-old male who, following resection of a Masaoka stag…

Multidisciplinary management of refractory Kawasaki disease with bilateral giant coronary artery aneurysms and latent tuberculosis infection: a case report focusing on immune–coagulation–infection crosstalk

BackgroundThe management of refractory Kawasaki disease (KD) with giant coronary artery aneurysms (CAAs) complicated by latent tuberculosis infection (LTBI) represents a formidable “triple challenge”: it requires balancing aggressive inflammation contr…

Neurological graft-versus-host disease with MOG antibody positivity after allogeneic stem cell transplantation: a case report

BackgroundCentral nervous system (CNS) involvement is recognized as a distinct manifestation of chronic GVHD (cGVHD). Myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) is an autoimmune disorder targeting the CNS. Therefore, the oc…

Immune profiling-informed immunomodulation associated with gestational extension in early-onset preeclampsia with monochorionic twins: a case report

BackgroundEarly-onset preeclampsia (EOPE) is associated with placental malperfusion and systemic endothelial dysfunction. Maternal immune dysregulation has been implicated in EOPE, but immune findings obtained during severe disease are descriptive and …

Case Report: Switching secukinumab to bimekizumab in diffuse cutaneous systemic sclerosis after autologous hematopoietic stem cell transplantation: a case follow-up

Diffuse cutaneous systemic sclerosis (dcSSc) is a heterogeneous autoimmune disease characterized by progressive skin fibrosis, vasculopathy and variable organ involvement. Our recent case report about this patient described clinical improvement under I…

Viral encephalitis related to adalimumab in a 16-year-old Crohn’s disease patient: case report and literature review

Tumor necrosis factor-alpha (TNF-α) inhibitors are extensively utilized in inflammatory bowel disease (IBD). Adalimumab (ADA), a TNF-α inhibitor, appears to be an effective and safe option for pediatric Crohn’s disease (CD), but the potential risk of o…

Case Report: Overlap syndrome of anti–NMDA receptor encephalitis and MOG-associated disease in a pediatric patient—literature insights

Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) and anti-N-methyl-D- aspartate receptor (NMDAR) encephalitis pediatric cases are especially challenging due to phenotypic variability, limited literature, and the absence of standardized trea…

Intra-arterial infusion of bevacizumab for the treatment of peritoneal metastatic high-grade renal cell carcinoma: a case report

BackgroundMetastatic renal cell carcinoma (mRCC) is a common type of urologic malignancy with limited systemic treatment, especially for extensive metastatic lesions in the peritoneum and greater omentum.Case reportA 35-year-old male patient was admitt…

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