Nature Reviews Immunology, Published online: 09 December 2025; doi:10.1038/s41577-025-01257-zRespiratory infections in early life combine with genetic and maternal factors to drive asthma development in childhood.
Nature Reviews Immunology, Published online: 09 December 2025; doi:10.1038/s41577-025-01260-4Besides killing infected or transformed cells, interferon-activated natural killer cells can kill T follicular helper cells and may contribute…
Nature Reviews Immunology, Published online: 08 December 2025; doi:10.1038/s41577-025-01259-xA preprint by Breuer et al. reports that type I IFN signalling in tumour cells promotes lymph node metastasis but suppresses metastasis to dis…
Nature Reviews Immunology, Published online: 02 December 2025; doi:10.1038/s41577-025-01256-0A study in Nature reports that heterotypic T cell clusters identifed in clinical samples of melanoma metastases are biologically relevant to t…
Nature Reviews Immunology, Published online: 26 November 2025; doi:10.1038/s41577-025-01253-3A preprint by Bockman et al. reports a cDC2-CD4+ T cell axis that mediates local tumour control after ablation of intratumoral Treg cells, wit…
Nature Reviews Immunology, Published online: 26 November 2025; doi:10.1038/s41577-025-01251-5A preprint by Zhijie et al. identifies somatic mutations in TYK2 that are enriched in tumour-infiltrating lymphocytes and associated with an i…
Nature Reviews Immunology, Published online: 26 November 2025; doi:10.1038/s41577-025-01252-4A preprint by Liu et al. shows proof-of-concept for a treatment for autoimmune diseases such as SLE using synthetic immune receptor T cells th…
Nature Reviews Immunology, Published online: 18 November 2025; doi:10.1038/s41577-025-01238-2This Consensus Statement clarifies the existing subset-based nomenclature for T cells. Furthermore, it proposes an alternative modular nomencl…
Nature Reviews Immunology, Published online: 18 November 2025; doi:10.1038/s41577-025-01246-2This poster provides an overview of the current subset-based nomenclature for T cells and a newly proposed modular nomenclature for T cells. I…
Nature Reviews Immunology, Published online: 14 November 2025; doi:10.1038/s41577-025-01245-3Short-chain fatty acids generated by the gut microbiota can support T cell ‘stemness’ and lead to improved cancer immunotherapy outcomes.
