Nature Reviews Immunology, Published online: 04 April 2025; doi:10.1038/s41577-025-01169-yNelson et al. report that lung-resident IgG1+ memory B cells class-switch to IgE to mediate airway hypersensitivity in asthma.
Nature Reviews Immunology, Published online: 01 April 2025; doi:10.1038/s41577-025-01149-2Regulatory T (Treg) cells have an important role in the maintenance of immune tolerance and continuously circulate in the body. During this migra…
Nature Reviews Immunology, Published online: 01 April 2025; doi:10.1038/s41577-025-01168-zIn this Tools of the Trade article, Sofia Bustamante Eguiguren (from the Dushek and van der Merwe labs) describes CombiCells, which can be custom…
Nature Reviews Immunology, Published online: 28 March 2025; doi:10.1038/s41577-025-01164-3A preprint by Dolci et al. reports that tumour-associated macrophages secrete SPP1 to drive neurite outgrowth, promoting tumour innervation and s…
Nature Reviews Immunology, Published online: 28 March 2025; doi:10.1038/s41577-025-01163-4A preprint by Liu et al. shows that resident tissue macrophages in the conventional outflow tract regulate intraocular pressure in the steady state.
Nature Reviews Immunology, Published online: 27 March 2025; doi:10.1038/s41577-025-01165-2A preprint by Farias et al. shows that the type I interferon response to respiratory syncytial virus infection reduces lung metastasis of breast …
Nature Reviews Immunology, Published online: 20 March 2025; doi:10.1038/s41577-025-01150-9Immunoglobulins sample vast swathes of primary sequence and conformational space to generate and select B cell clones with exquisite selectivity …
Nature Reviews Immunology, Published online: 19 March 2025; doi:10.1038/s41577-025-01155-4In this Review, the authors explain how post-translational protein modification by the small ubiquitin-like modifier (SUMO) family is emerging as…
Nature Reviews Immunology, Published online: 17 March 2025; doi:10.1038/s41577-025-01160-7Drugs like aspirin can enhance the anti-metastatic activity of T cells by blocking a platelet-mediated pathway of suppression.
Nature Reviews Immunology, Published online: 05 March 2025; doi:10.1038/s41577-025-01157-2A preprint by Eislmayr et al. shows that macrophages rather than neutrophils are a key factor in controlling Shigella infection.
