BackgroundInvestigating the relationship between gut microbiota and Rheumatic Valve Disease (RVD) is crucial for understanding the disease’s etiology and developing effective interventions. Our study adopts a novel approach to examine the potential cau…
BackgroundPsoriasis is a chronic dermatological condition characterized by a complex pathogenesis that impacts approximately 3% of adults in the United States and brings enormous social burdens. For many diseases, the systemic immune-inflammatory index…
Systemic lupus erythematosus (SLE) is classified by instinctual classification criteria. A valid proclamation is that these formally accepted SLE classification criteria legitimate the syndrome as being difficult to explain and therefore enigmatic. SLE…
IntroductionThis study examined the impact of 5’-(N- ethylcarboxamido)adenosine (NECA) in the peripheral blood of healthy individuals, those with diabetes mellitus, diabetic retinopathy (DR), and C57BL/6 mice, both in vivo and in vitro.MethodsEnzyme-li…
Nature Reviews Immunology, Published online: 03 June 2024; doi:10.1038/s41577-024-01049-xThis Comment discusses the potential effects of ultra-processed foods (UPFs) on the immune system independently of obesity, by which UPFs might dy…
Nature Reviews Immunology, Published online: 03 June 2024; doi:10.1038/s41577-024-01040-6This Review provides a guide to the memory cells of the adaptive immune system, comprising memory T cells, memory B cells and plasma cells; it cov…
Nature Reviews Immunology, Published online: 03 June 2024; doi:10.1038/s41577-024-01035-3Recent clinical studies show that chimeric antigen receptor (CAR) T cells, best known for treating B cell malignancies, can be used to treat patie…
IntroductionThe standard treatment for preventing rejection in vascularized composite allotransplantation (VCA) currently relies on systemic immunosuppression, which exposes the host to well-known side effects. Locally administered immunosuppression st…
BackgroundThe impact of chronic hepatic infection on antigen non-specific immune cells in circulation remains poorly understood. We reported lasting global hyperfunction of peripheral CD8 T cells in HCV-infected individuals with cirrhosis. Whether gene…
IntroductionAcute respiratory distress syndrome (ARDS) is a major cause of death among critically ill patients in intensive care settings, underscoring the need to identify biomarkers capable of predicting ARDS patient clinical status and prognosis at …
