Vitamin D-dependent microbiota-enhancing tumor immunotherapy
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Nature Reviews Immunology, Published online: 31 May 2024; doi:10.1038/s41577-024-01053-1CD8+ T cells become exhausted when exposed to the mechanical forces of stiff solid tumours, owing to signalling through the transcription factor OSR2.
Cellular & Molecular Immunology, Published online: 31 May 2024; doi:10.1038/s41423-024-01179-1TRIM33 plays a critical role in regulating dendritic cell differentiation and homeostasis by modulating Irf8 and Bcl2l11 transcription
Cellular & Molecular Immunology, Published online: 31 May 2024; doi:10.1038/s41423-024-01168-4Legacy of the discovery of the T-cell receptor: 40 years of shaping basic immunology and translational work to develop novel therapies
Science Immunology, Volume 9, Issue 95, May 2024.
Science Immunology, Volume 9, Issue 95, May 2024.
Science Immunology, Volume 9, Issue 95, May 2024.
BackgroundMast cells are critically involved in IgE-mediated diseases, e.g., allergies and asthma. Human mast cells are heterogeneous, and mast cells from different anatomical sites have been shown to respond differently to certain stimuli and drugs. T…