Coming of age: the formation and function of age-associated B cells
Cellular & Molecular Immunology, Published online: 26 February 2024; doi:10.1038/s41423-024-01143-zComing of age: the formation and function of age-associated B cells
Publicaciones
Inactivation of TGF-β signaling in CAR-T cells
Cellular & Molecular Immunology, Published online: 26 February 2024; doi:10.1038/s41423-023-01123-9Inactivation of TGF-β signaling in CAR-T cells
ComplexEye: a multi-lens array microscope for high-throughput cell migration analysis
Nature Reviews Immunology, Published online: 23 February 2024; doi:10.1038/s41577-024-01009-5In this Tools of the Trade article, Zülal Cibir and Matthias Gunzer introduce their multi-lens array microscope called ComplexEye that allows …
SARS-CoV-2-infection- and vaccine-induced antibody responses are long lasting with an initial waning phase followed by a stabilization phase
SARS-CoV-2 mRNA-based vaccine-induced immunity is thought to wane quickly based on short-term studies. Using longitudinal data, Srivastava et al. find that participants with hybrid immunity show faster, higher antibody responses after initial vaccinati…
Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety
While Na+/K+-ATPase (NKA) plays important roles in the CNS, its role in microglia is unclear. Huang et al. find that NKAα1 inhibits microglia activation by forming a complex with P2X7R. Stress decreases membrane expression of NKAα1, facilitating P2X7R-…
CD4<sup>+</sup> T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors
Cellular & Molecular Immunology, Published online: 21 February 2024; doi:10.1038/s41423-024-01133-1CD4+ T cells produce IFN-I to license cDC1s for induction of cytotoxic T-cell activity in human tumors
The conneXion between sex and immune responses
Nature Reviews Immunology, Published online: 21 February 2024; doi:10.1038/s41577-024-00996-9Immune responses to pathogens and self-antigens show sex-based differences, with female individuals generally more susceptible to autoimmunity…
Unsynchronized butyrophilin molecules dictate cancer cell evasion of Vγ9Vδ2 T-cell killing
Cellular & Molecular Immunology, Published online: 20 February 2024; doi:10.1038/s41423-024-01135-zUnsynchronized butyrophilin molecules dictate cancer cell evasion of Vγ9Vδ2 T-cell killing
Mechanistic insights from inflammasome structures
Nature Reviews Immunology, Published online: 19 February 2024; doi:10.1038/s41577-024-00995-wThis Review highlights new insights into the biology of inflammasomes from the perspective of structural and mechanistic studies, revealing ho…
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases
Nature Reviews Immunology, Published online: 19 February 2024; doi:10.1038/s41577-024-00994-xIn this Review, the authors discuss the origins of regulatory T (Treg) cells in the periphery and the mechanisms by which Treg cells are induc…