Effects of breathing training on walking ability and quality of life in patients with multiple sclerosis: systematic review and meta-analysis of randomized controlled trials

BackgroundIn recent years, an increasing number of studies have investigated the effects of breathing exercises on walking ability and quality of life in patients with multiple sclerosis (MS). However, the results of these studies are inconsistent. Thi…

Trends and hotspots in research related to tumor immune escape: bibliometric analysis and future perspectives

BackgroundTumor immune escape, a defining hallmark of malignant tumors, enables cancer cells to thrive within the host by evading detection and attack by the immune system. While immune checkpoint inhibitors, such as PD-1/PD-L1 antibodies, have deliver…

Temporal dynamics of early inflammatory markers after professional dental cleaning: a meta-analysis and spline-based meta-regression of TNF-α, IL-1β, IL-6, and (hs)CRP

IntroductionChronic periodontitis is linked to systemic inflammation and cardiovascular risk, yet the temporal trajectory and magnitude of systemic cytokine reduction following nonsurgical-periodontal-therapy (NSPT) remain underexplored. We conducted a…

Adipose-derived mesenchymal stem cells and their derivatives in inflammatory skin diseases: a systematic review

Adipose-derived mesenchymal stem cells (ADMSCs) offer a multifaceted approach to treating immune-mediated skin diseases by modulating the immune system and promoting tissue regeneration. Specifically, their ability to differentiate into multiple cell t…

Evaluating the efficacy, safety, and immunogenicity of FDA-approved RSV vaccines: a systematic review of Arexvy, Abrysvo, and mResvia

BackgroundRespiratory Syncytial Virus (RSV) poses a major health threat to older adults, pregnant women, and high-risk populations. We systematically evaluated the efficacy, immunogenicity, and safety of three FDA-approved RSV vaccines: Arexvy, Abrysvo…

Effects of different exercise prescription parameters on metabolic and inflammatory biomarkers in cancer patients: a systematic review, meta-analysis, and meta-regression

ObjectiveThis study aimed to systematically evaluate the effects of exercise interventions on metabolic and inflammatory biomarkers in cancer patients, and to identify potential dose–response relationships and modulatory mechanisms using Robust Varianc…

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