Efficacy and safety of CD19 combined with CD22 or CD20 chimeric antigen receptor T-cell therapy for hematological malignancies

BackgroundCD19 combined with CD22 or CD20 therapy is a promising immunotherapy approach for the treatment of hematological malignancies. Dual-targeted CD19/CD22 CAR T and CD19/CD22 CAR T-cell therapy are currently being evaluated in clinical trials, an…

Comparisons of liver transplant from DCD outcomes in high-utilization centers versus low-utilization centers in the US: a systematic review and meta-analysis

Purpose/ObjectiveDonation after Cardiac Death (DCD) grafts are considered to be inferiors compared to Donation after Brain Death (DBD) grafts. Consequently, many transplant centers employ highly selective criteria for utilizing DCD, while others use th…

Global research status and frontiers on ferroptosis in hepatocellular carcinoma: a comprehensive bibliometric and visualized analysis

ObjectiveThe purpose of this study was to analyze the research hotspots and future trends in the field of ferroptosis in hepatocellular carcinoma in the past 10 years by using bibliometrics and visualization software, and to provide reference for futur…

The neoadjuvant immunotherapy for non-metastatic mismatch repair-deficient colorectal cancer: a systematic review

BackgroundImmunotherapy has become the first-line treatment for metastatic mismatch repair deficient (dMMR) colorectal cancer. The efficacy and safety of neoadjuvant immunotherapy for the treatment of non-metastatic dMMR colorectal cancer remain unclea…

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