BackgroundSiglec-15 has emerged as a novel immune checkpoint molecule and a potential therapeutic target in solid tumors. Previous studies reported inconsistent prognostic significance of tumoral Siglec-15 expression across cancer types. We therefore c…
ObjectiveMembranous nephropathy (MN) constitutes an autoimmune glomerular disorder and represents the most frequent etiology of primary nephrotic syndrome in adults. Although obinutuzumab exhibits favorable efficacy in managing refractory MN, outcomes …
BackgroundStaphylococcus aureus (S. aureus) has emerged as a significant global public health threat, owing to its complex immune evasion strategies. Despite growing research output in this field, a comprehensive, data-driven bibliometric analysis deli…
ObjectiveAutoimmune thyroiditis (AIT) patients frequently present with coexisting autoimmune diseases (ADs), adding complexity to management and outcomes. Although this field has been extensively explored, there is a paucity of bibliometric analyses ca…
Backgrounds and aimsStroke-associated pneumonia (SAP) is a major infectious complication that increases mortality after stroke. Stroke-induced immunosuppression has been proposed as a key driver of SAP, supporting the rationale for immunomodulation. Th…
IntroductionAdvanced gastric and gastroesophageal junction (G/GEJ) adenocarcinomas are characterized by an aggressive course and a very poor prognosis. Due to the limited benefit of immunotherapy in patients with HER2-negative tumors, new therapeutic t…
PurposedNatural Killer cell kinetics and Killer-cell immunoglobulin-like receptors (KIRs) are increasingly recognized for their role during allogeneic hematopoietic stem cell transplantation (allo-HSCT), but the prognostic impact of donor KIR haplotype…
BackgroundTertiary lymphoid structures (TLSs) are increasingly regarded as important local immune niches in chronic inflammation and autoimmunity. However, a focused bibliometric overview of TLS research in autoimmune diseases is still lacking.MethodsP…
BackgroundPerioperative alterations in T lymphocyte subsets significantly impact tumor recurrence and postoperative recovery; therefore, identifying optimal strategies to maintain these immune parameters is essential for improving cancer surgery outcom…
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, yet clinical responses remain highly variable, and microbiome-associated findings lack reproducibility across studies. Increasing evidence implicates the gut microbiome in modulating …
