IntroductionPeripheral blood inflammatory markers (PBIMs) are widely used for prognostication of several malignancies, including gynecologic cancers. However, most studies do not report when PBIMs have been sampled, and the ones that do usually use pre…
ObjectiveDepression is one of the most common mental disorders and is the leading cause of disability worldwide. The objective of this systematic review was to synthesize the latest evidence from randomized controlled trials (RCTs) regarding the effect…
BackgroundOsteoarthritis, a common degenerative osteochondral disease, has a close relationship between its mechanism of Macrophage polarization. However, there are relatively few relevant studies in this field, and a more mature research system has no…
ObjectivesThis meta-analysis evaluated the direction and strength of associations between air pollution, emerging chemical pollutants, and systemic lupus erythematosus (SLE) incidence, clarifying distinct relationships by pollutant type.MethodBy utiliz…
IntroductionChimeric antigen receptor (CAR) T-cell therapy has revolutionized the treatment of relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL), yet challenges such as cytokine release syndrome (CRS), neurotoxicity (ICANS), and variable …
BackgroundAllergic diseases resulting from aberrant immune function are frequently observed in patients with inborn errors of immunity (IEI). However, the underlying monogenic disorders may not be initially diagnosed, which leads to delays in appropria…
BackgroundAsthma is a chronic respiratory disease influenced by genetic and environmental factors. Emerging evidence highlights epigenetics as a key regulatory mechanism in asthma development.ObjectiveThis research aimed to summarize current evidence o…
BackgroundVascular cognitive impairment (VCI) exhibits particularly high prevalence in East Asian populations. However, its pathogenesis remains elusive due to its multifactorial and complex nature. Emerging evidence highlights the microbiota-gut-brain…
BackgroundGrowing research reveals a relation of the neutrophil-to-lymphocyte ratio (NLR) to clinical outcomes of the esophageal cancer (EC) population undergoing neoadjuvant therapy. However, current findings remain inconclusive and somewhat controver…
IntroductionFluorescence Lifetime Imaging Microscopy (FLIM) is an imaging technique that allows for the visualization of the cellular microenvironment by measuring the decay time of endogenous fluorescent molecules. Its advent has allowed the acquisiti…
